Tissue Specificity | Detected in fibroblasts (at protein level). |
Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. |
Protein Name | TenascinTnCytotactinGmemGp 150-225Glioma-Associated-Extracellular Matrix AntigenHexabrachionJiMyotendinous AntigenNeuronectinTenascin-CTn-C |
Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000170Reactome: R-HSA-3000178Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Tenascin antibodyAnti-Tn antibodyAnti-Cytotactin antibodyAnti-Gmem antibodyAnti-Gp 150-225 antibodyAnti-Glioma-Associated-Extracellular Matrix Antigen antibodyAnti-Hexabrachion antibodyAnti-Ji antibodyAnti-Myotendinous Antigen antibodyAnti-Neuronectin antibodyAnti-Tenascin-C antibodyAnti-Tn-C antibodyAnti-TNC antibodyAnti-HXB antibody |
Information sourced from Uniprot.org