| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TEKT5 |
| Gene ID: | 146279 |
| Uniprot ID: | TEKT5_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TEKT5 (NP_653275.1). |
| Immunogen Sequence: | MEFLGTTQTASYCGPKKCCG LTSLPAVQAPVIQECYQPYY LPGYRYLNSWRPSLFYKIAN VQTCPDESTSTLRPPTILPT LRSALFSRYSPHDWDQSNQL QVRGAEASRLWASRLTDDSM RLLQDKDQLTHQMQEGTCRN LGQRLSDIGFWKSELSYELD RLLTENQNLETVKRRLECAA NEVNCPLQVALECLYHREKR IGIDLVHDNVEKNLIREVDL LKCCQEQMRKLAQRIDIQM |
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. |
| Function | Sperm-specific microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in flagellar axoneme. Forms an extensive interaction network in different conformations that reinforces the helix bundle composed by other tektin proteins (TEKT1 to TEKT4) and MIPs to anchor the tektin bundle onto the tubulin wall of A-tubule of the sperm flagellum. |
| Protein Name | Tektin-5 |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum Axoneme |
| Alternative Antibody Names | Anti-Tektin-5 antibodyAnti-TEKT5 antibody |
Information sourced from Uniprot.org
