| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-TdT (52-192aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ZM51 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:50‐100 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | DNTT |
| Gene ID: | 1791 |
| Uniprot ID: | TDT_HUMAN |
| Immunogen Region: | 52-192aa |
| Specificity: | Positive control: Thymus |
| Immunogen: | Recombinant fragment (around aa 52-192) of human DNTT protein |
| Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
| Protein Name | Dna NucleotidylexotransferaseTerminal Addition EnzymeTerminal DeoxynucleotidyltransferaseTerminal Transferase |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Nucleotidylexotransferase antibodyAnti-Terminal Addition Enzyme antibodyAnti-Terminal Deoxynucleotidyltransferase antibodyAnti-Terminal Transferase antibodyAnti-DNTT antibodyAnti-TDT antibody |
Information sourced from Uniprot.org
