Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-TdT (52-192aa) is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | ZM51 |
Conjugation: | Unconjugated |
Isotype: | IgG1/Kappa |
Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
Purification: | Affinity purified |
Dilution Range: | 1:50‐100 |
Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Gene Symbol: | DNTT |
Gene ID: | 1791 |
Uniprot ID: | TDT_HUMAN |
Immunogen Region: | 52-192aa |
Specificity: | Positive control: Thymus |
Immunogen: | Recombinant fragment (around aa 52-192) of human DNTT protein |
Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
Protein Name | Dna NucleotidylexotransferaseTerminal Addition EnzymeTerminal DeoxynucleotidyltransferaseTerminal Transferase |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Dna Nucleotidylexotransferase antibodyAnti-Terminal Addition Enzyme antibodyAnti-Terminal Deoxynucleotidyltransferase antibodyAnti-Terminal Transferase antibodyAnti-DNTT antibodyAnti-TDT antibody |
Information sourced from Uniprot.org