Anti-TDO2 antibody (167-184) (STJ115148)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TDO2 (167-184) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TDO2 |
| Gene ID | 6999 |
| Uniprot ID | T23O_HUMAN |
| Immunogen Region | 167-184 |
| Immunogen Sequence | GHVRDERNMLKVVSRMHRVS VILKLLVQQFSILETMTALD FNDFREYLSPASGFQSLQFR LLENKIGVLQNMRVPYNRRH YRDNFKGEENELLLKSEQEK TLLELVEAWLERTPGLEPHG FNFWGKLEKNITRGLEEEFI RIQAKEESEEKEEQVAEFQK QKEVLLSLFDEKRHEHLLSK GERRLSYRALQGALMIYFYR |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TDO2 (NP_005642.1). |
Additional Info
| Function | Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. |
| Protein Name | Tryptophan 2 -3-DioxygenaseTdoTryptamin 2 -3-DioxygenaseTryptophan OxygenaseToTrpoTryptophan PyrrolaseTryptophanase |
| Database Links | Reactome: R-HSA-71240 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tryptophan 2 -3-Dioxygenase antibodyAnti-Tdo antibodyAnti-Tryptamin 2 -3-Dioxygenase antibodyAnti-Tryptophan Oxygenase antibodyAnti-To antibodyAnti-Trpo antibodyAnti-Tryptophan Pyrrolase antibodyAnti-Tryptophanase antibodyAnti-TDO2 antibodyAnti-TDO antibody |
Information sourced from Uniprot.org