| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transcription factor 7-like 1 (321-370 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TCF7L1 |
| Gene ID: |
83439 |
| Uniprot ID: |
TF7L1_HUMAN |
| Immunogen Region: |
321-370 aa |
| Specificity: |
TCF-3 Polyclonal Antibody detects endogenous levels of TCF-3 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human TCF7L1 at the amino acid range 321-370 |
| Function | Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. Down-regulates NQO1, leading to increased mitomycin c resistance. |
| Protein Name | Transcription Factor 7-Like 1Hmg Box Transcription Factor 3Tcf-3 |
| Database Links | Reactome: R-HSA-201722Reactome: R-HSA-3769402Reactome: R-HSA-4086398Reactome: R-HSA-4411364Reactome: R-HSA-4641265Reactome: R-HSA-8951430 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor 7-Like 1 antibodyAnti-Hmg Box Transcription Factor 3 antibodyAnti-Tcf-3 antibodyAnti-TCF7L1 antibodyAnti-TCF3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
