• Western blot analysis of lysates from HUVEC, COLO205, and 293 cells, using TCF7 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using TCF-1 Polyclonal Antibody diluted at 1：1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-TCF7 antibody (10-59 aa) (STJ95942)

SKU:
STJ95942

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transcription factor 7 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TCF7
Gene ID: 6932
Uniprot ID: TCF7_HUMAN
Immunogen Region: 10-59 aa
Specificity: TCF-1 Polyclonal Antibody detects endogenous levels of TCF-1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TCF7 at the amino acid range 10-59
Function Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages. Required for the development of natural killer receptor-positive lymphoid tissue inducer T-cells. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes.
Protein Name Transcription Factor 7
Tcf-7
T-Cell-Specific Transcription Factor 1
T-Cell Factor 1
Tcf-1
Database Links Reactome: R-HSA-201722
Reactome: R-HSA-3769402
Reactome: R-HSA-4086398
Reactome: R-HSA-4411364
Reactome: R-HSA-4641265
Reactome: R-HSA-8951430
Reactome: R-HSA-9754189
Reactome: R-HSA-9796292
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor 7 antibody
Anti-Tcf-7 antibody
Anti-T-Cell-Specific Transcription Factor 1 antibody
Anti-T-Cell Factor 1 antibody
Anti-Tcf-1 antibody
Anti-TCF7 antibody
Anti-TCF1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance