| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transcription elongation factor A protein-like 7 (34-84 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCEAL7 |
| Gene ID: | 56849 |
| Uniprot ID: | TCAL7_HUMAN |
| Immunogen Region: | 34-84 aa |
| Specificity: | This antibody detects endogenous levels of human TCEAL7 |
| Immunogen: | Synthesized peptide derived from the human TCEAL7 at the amino acid range 34-84 |
| Function | Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines. |
| Protein Name | Transcription Elongation Factor A Protein-Like 7Tcea-Like Protein 7Transcription Elongation Factor S-Ii Protein-Like 7 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Elongation Factor A Protein-Like 7 antibodyAnti-Tcea-Like Protein 7 antibodyAnti-Transcription Elongation Factor S-Ii Protein-Like 7 antibodyAnti-TCEAL7 antibody |
Information sourced from Uniprot.org