| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Brachyury (Internal Region) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS + 0.02% NaN3 |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBXT |
| Gene ID: | 6862 |
| Uniprot ID: | TBXT_HUMAN |
| Immunogen Region: | Internal Region |
| Specificity: | Reacts with an internal sequence of the human Brachyury protein. Sequence is 80% identical in mouse and rat. |
| Immunogen: | Synthetic peptide corresponding to amino acids from an internal sequence of the human Brachyury protein |
| Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
| Protein Name | T-Box Transcription Factor T Brachyury Protein Protein T |
| Database Links | Reactome: R-HSA-9733709 Reactome: R-HSA-9754189 Reactome: R-HSA-9758919 Reactome: R-HSA-9793380 Reactome: R-HSA-9796292 Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Transcription Factor T antibody Anti-Brachyury Protein antibody Anti-Protein T antibody Anti-TBXT antibody Anti-T antibody |
Information sourced from Uniprot.org