| Short Description : | Mouse monoclonal anti-F-box-like/WD repeat-containing protein TBL1Y for use in WB in Human, Mouse, Rat, Dog and Pig samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Mouse |
| Reactivity: | Human/Mouse/Rat/Dog/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:1000-1:2000 |
| Formulation: | Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBL1Y |
| Gene ID: | 90665 |
| Uniprot ID: | TBL1Y_HUMAN |
| Immunogen: | Purified recombinant human TBL1Y protein fragments expressed in E.coli. |
| Specificity: | TBL1Y Monoclonal Antibody detects endogenous levels of TBL1Y protein. |
| Function | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. |
| Protein Name | F-Box-Like/Wd Repeat-Containing Protein Tbl1yTransducin Beta-Like Protein 1yTransducin-Beta-Like Protein 1 - Y-Linked |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-F-Box-Like/Wd Repeat-Containing Protein Tbl1y antibodyAnti-Transducin Beta-Like Protein 1y antibodyAnti-Transducin-Beta-Like Protein 1 - Y-Linked antibodyAnti-TBL1Y antibodyAnti-TBL1 antibody |
Information sourced from Uniprot.org
