| Host: | Mouse |
| Applications: | WB/ICC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-F-box-like/WD repeat-containing protein TBL1X is suitable for use in Western Blot and Immunocytochemistry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | 4H2-D5-E9 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000ICC 1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBL1X |
| Gene ID: | 6907 |
| Uniprot ID: | TBL1X_HUMAN |
| Specificity: | This antibody detects endogenous levels of TBL1X and does not cross-react with related proteins. |
| Immunogen: | Purified recombinant human TBL1 protein fragments expressed in E.coli. |
| Function | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. |
| Protein Name | F-Box-Like/Wd Repeat-Containing Protein Tbl1xSmap55Transducin Beta-Like Protein 1xTransducin-Beta-Like Protein 1 - X-Linked |
| Database Links | Reactome: R-HSA-1368082Reactome: R-HSA-1368108Reactome: R-HSA-1989781Reactome: R-HSA-2122947Reactome: R-HSA-2151201Reactome: R-HSA-2426168Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-3214815Reactome: R-HSA-350054Reactome: R-HSA-381340Reactome: R-HSA-400206Reactome: R-HSA-400253Reactome: R-HSA-9022537Reactome: R-HSA-9022692Reactome: R-HSA-9029569Reactome: R-HSA-9609690Reactome: R-HSA-9707564Reactome: R-HSA-9707616 |
| Cellular Localisation | NucleusColocalized With Mecp2 To The Heterochromatin Foci |
| Alternative Antibody Names | Anti-F-Box-Like/Wd Repeat-Containing Protein Tbl1x antibodyAnti-Smap55 antibodyAnti-Transducin Beta-Like Protein 1x antibodyAnti-Transducin-Beta-Like Protein 1 - X-Linked antibodyAnti-TBL1X antibodyAnti-TBL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
