| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBC1D1 |
| Gene ID: | 23216 |
| Uniprot ID: | TBCD1_HUMAN |
| Immunogen Region: | 1069-1168 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1069-1168 of human TBC1D1 (NP_055988.2). |
| Immunogen Sequence: | IDSSPLSDNQRMDKLEKTNS SLRKQNLDLLEQLQVANGRI QSLEATIEKLLSSESKLKQA MLTLELERSALLQTVEELRR RSAEPSDREPECTQPEPTGD |
| Post Translational Modifications | Insulin-stimulated phosphorylation by AKT family kinases stimulates SLC2A4/GLUT4 translocation. |
| Function | May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells. |
| Protein Name | Tbc1 Domain Family Member 1 |
| Database Links | Reactome: R-HSA-1445148 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Tbc1 Domain Family Member 1 antibodyAnti-TBC1D1 antibodyAnti-KIAA1108 antibody |
Information sourced from Uniprot.org