| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAS2R38 |
| Gene ID: | 5726 |
| Uniprot ID: | T2R38_HUMAN |
| Immunogen Region: | 150-250 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human TAS2R38 (NP_789787.4). |
| Immunogen Sequence: | CSCICTVLCVWCFFSRPHFT VTTVLFMNNNTRLNWQIKDL NLFYSFLFCYLWSVPPFLLF LVSSGMLTVSLGRHMRTMKV YTRNSRDPSLEAHIKALKSL V |
| Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in testis. |
| Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Protein Name | Taste Receptor Type 2 Member 38 T2r38 Ptc Bitter Taste Receptor Taste Receptor Type 2 Member 61 T2r61 |
| Database Links | Reactome: R-HSA-418594 Reactome: R-HSA-420499 Reactome: R-HSA-9717207 |
| Cellular Localisation | Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 38 antibody Anti-T2r38 antibody Anti-Ptc Bitter Taste Receptor antibody Anti-Taste Receptor Type 2 Member 61 antibody Anti-T2r61 antibody Anti-TAS2R38 antibody Anti-PTC antibody |
Information sourced from Uniprot.org