| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAS2R10 |
| Gene ID: | 50839 |
| Uniprot ID: | T2R10_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TAS2R10 (NP_076410.1). |
| Immunogen Sequence: | TSLSIFYFLKIANFSNYIFL WLKSRTNMVLPFMIVFLLIS SLLNFAYIAKILNDYKTKND TVWDLNMYKSEYFIKQILLN LGVIFFFTLSLITCIFLIIS L |
| Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. |
| Function | Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. |
| Protein Name | Taste Receptor Type 2 Member 10T2r10Taste Receptor Family B Member 2Trb2 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499Reactome: R-HSA-9717207 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 10 antibodyAnti-T2r10 antibodyAnti-Taste Receptor Family B Member 2 antibodyAnti-Trb2 antibodyAnti-TAS2R10 antibody |
Information sourced from Uniprot.org