| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | TAPBPL |
| Gene ID: | 55080 |
| Uniprot ID: | TPSNR_HUMAN |
| Immunogen Region: | 19-170 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-170 of human TAPBPL (NP_060479.3). |
| Immunogen Sequence: | AETKPHPAEGQWRAVDVVLD CFLAKDGAHRGALASSEDRA RASLVLKQVPVLDDGSLEDF TDFQGGTLAQDDPPIIFEAS VDLVQIPQAEALLHADCSGK EVTCEISRYFLQMTETTVKT AAWFMANMQVSGGGPSISLV MKTPRVTKNEAL |
| Function | Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). |
| Protein Name | Tapasin-Related ProteinTapasin-RTap-Binding Protein-LikeTap-Binding Protein-Related ProteinTapbp-RTapasin-Like |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum MembraneMicrosome MembraneGolgi Apparatus MembraneMainly Found In Endoplasmic Reticulum But A Minority Is Found On The Cell Surface |
| Alternative Antibody Names | Anti-Tapasin-Related Protein antibodyAnti-Tapasin-R antibodyAnti-Tap-Binding Protein-Like antibodyAnti-Tap-Binding Protein-Related Protein antibodyAnti-Tapbp-R antibodyAnti-Tapasin-Like antibodyAnti-TAPBPL antibody |
Information sourced from Uniprot.org