| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:10-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TALDO1 |
| Gene ID: | 6888 |
| Uniprot ID: | TALDO_HUMAN |
| Immunogen Region: | 1-337 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-337 of human TALDO1 (NP_006746.1). |
| Immunogen Sequence: | MSSSPVKRQRMESALDQLKQ FTTVVADTGDFHAIDEYKPQ DATTNPSLILAAAQMPAYQE LVEEAIAYGRKLGGSQEDQI KNAIDKLFVLFGAEILKKIP GRVSTEVDARLSFDKDAMVA RARRLIELYKEAGISKDRIL IKLSSTWEGIQAGKELEEQH GIHCNMTLLFSFAQAVACAE AGVTLISPFVGRILDWHVAN TDKKSYEPLEDPGVKSVTKI YNYYKKFSYKTIVMGASFR |
| Function | Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. Not only acts as a pentose phosphate pathway enzyme, but also affects other metabolite pathways by altering its subcellular localization between the nucleus and the cytoplasm. |
| Protein Name | Transaldolase |
| Database Links | Reactome: R-HSA-163754 Reactome: R-HSA-6791055 Reactome: R-HSA-6791462 Reactome: R-HSA-71336 Reactome: R-HSA-8950505 Reactome: R-HSA-9818028 |
| Cellular Localisation | Isoform 1: Nucleus Cytoplasm Shuttles Between The Nucleus And The Cytoplasm Actively Transported Into The Nucleus In An Importin Alpha/Beta-Dependent Manner Exported Into The Cytoplasm By Crm1 Isoform 2: Cytoplasm Imported Into The Nucleus When Incorporated In Isoform 1/Isoform 2 Homodimer |
| Alternative Antibody Names | Anti-Transaldolase antibody Anti-TALDO1 antibody Anti-TAL antibody Anti-TALDO antibody Anti-TALDOR antibody |
Information sourced from Uniprot.org
