Anti-TAF6L antibody (1-200) (STJ116581)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TAF6L (1-200) antibody for use in WB, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TAF6L |
| Gene ID | 10629 |
| Uniprot ID | TAF6L_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MSEREERRFVEIPRESVRLM AESTGLELSDEVAALLAEDV CYRLREATQNSSQFMKHTKR RKLTVEDFNRALRWSSVEAV CGYGSQEALPMRPAREGELY FPEDREVNLVELALATNIPK GCAETAVRVHVSYLDGKGNL APQGSVPSAVSSLTDDLLKY YHQVTRAVLGDDPQLMKVAL QDLQTNSKIGALLPYFVYVV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TAF6L (NP_006464.1). |
Additional Info
| Function | Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF5L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state. Functions with MYC to activate target gene expression through RNA polymerase II pause release. |
| Protein Name | Taf6-Like Rna Polymerase Ii P300/Cbp-Associated Factor-Associated Factor 65 Kda Subunit 6lTaf6lPcaf-Associated Factor 65-AlphaPaf65-Alpha |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Taf6-Like Rna Polymerase Ii P300/Cbp-Associated Factor-Associated Factor 65 Kda Subunit 6l antibodyAnti-Taf6l antibodyAnti-Pcaf-Associated Factor 65-Alpha antibodyAnti-Paf65-Alpha antibodyAnti-TAF6L antibodyAnti-PAF65A antibody |
Information sourced from Uniprot.org