| Function | The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF3 forms the TFIID-A module together with TAF5 and TBP. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The TAF3-TBPL2 complex replaces TFIID at specific promoters at an early stage in the differentiation process. |
| Protein Name | Transcription Initiation Factor Tfiid Subunit 3140 Kda Tata Box-Binding Protein-Associated FactorTbp-Associated Factor 3Transcription Initiation Factor Tfiid 140 Kda SubunitTaf(Ii140Taf140Tafii-140Tafii140 |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6804756Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Initiation Factor Tfiid Subunit 3 antibodyAnti-140 Kda Tata Box-Binding Protein-Associated Factor antibodyAnti-Tbp-Associated Factor 3 antibodyAnti-Transcription Initiation Factor Tfiid 140 Kda Subunit antibodyAnti-Taf(Ii140 antibodyAnti-Taf140 antibodyAnti-Tafii-140 antibodyAnti-Tafii140 antibodyAnti-TAF3 antibody |
Information sourced from Uniprot.org
