| Host: | Mouse |
| Applications: | WB/ICC/IP |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Trop-2/TACSTD2 (Extracellular region) is suitable for use in Western Blot, Immunocytochemistry and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | M005 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:1000ICC 1:100IP 1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TACSTD2 |
| Gene ID: | 4070 |
| Uniprot ID: | TACD2_HUMAN |
| Immunogen Region: | Extracellular region |
| Specificity: | Clone M005 detects a 50-65 kDa* band corresponding to the molecular mass of Trop-2 on SDS-PAGE immunoblots of native human A431, MDA-MB-231, and MCF-7 cell lysates. The antibody also detects denatured Trop-2, but with less affinity. Lower dilutions o |
| Immunogen: | Clone M005 was generated from a proprietary antigen related to the extracellular region of human Trop-2 from the A431 epidermoid carcinoma cell line. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | May function as a growth factor receptor. |
| Protein Name | Tumor-Associated Calcium Signal Transducer 2Cell Surface Glycoprotein Trop-2Membrane Component Chromosome 1 Surface Marker 1Pancreatic Carcinoma Marker Protein Ga733-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor-Associated Calcium Signal Transducer 2 antibodyAnti-Cell Surface Glycoprotein Trop-2 antibodyAnti-Membrane Component Chromosome 1 Surface Marker 1 antibodyAnti-Pancreatic Carcinoma Marker Protein Ga733-1 antibodyAnti-TACSTD2 antibodyAnti-GA733-1 antibodyAnti-M1S1 antibodyAnti-TROP2 antibody |
Information sourced from Uniprot.org