| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Substance-K receptor (301-350) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TACR2 |
| Gene ID: | 6865 |
| Uniprot ID: | NK2R_HUMAN |
| Immunogen Region: | 301-350 |
| Specificity: | NK-2R Polyclonal Antibody detects endogenous levels of NK-2R protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NK2R. AA range:301-350 |
| Function | This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. |
| Protein Name | Substance-K ReceptorSkrNk-2 ReceptorNk-2rNeurokinin A ReceptorTachykinin Receptor 2 |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Substance-K Receptor antibodyAnti-Skr antibodyAnti-Nk-2 Receptor antibodyAnti-Nk-2r antibodyAnti-Neurokinin A Receptor antibodyAnti-Tachykinin Receptor 2 antibodyAnti-TACR2 antibodyAnti-NK2R antibodyAnti-NKNAR antibodyAnti-TAC2R antibody |
Information sourced from Uniprot.org
