Host: | Mouse |
Applications: | FC/IP/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-T-Cell receptor is suitable for use in Flow Cytometry, Immunoprecipitation and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | TRIM-04 |
Conjugation: | Unconjugated |
Isotype: | IgG2a |
Formulation: | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
Concentration: | 1 mg/mL |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Recombinant intracellular domain (aa 29-186) of human TRIM. |
Background | TRIM (T cell receptor-interacting molecule) , also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear. |
Information sourced from Uniprot.org