Anti-T-Cell receptor antibody [TRIM-04] (STJ16100480)

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STJ16100480-01
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Short Description :Mouse monoclonal anti-T-Cell receptor for use in FC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/IP/WB
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :TRIM-04
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:1 mg/mL
Formulation:Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Immunogen:Recombinant intracellular domain (aa 29-186) of human TRIM.
Background TRIM (T cell receptor-interacting molecule) , also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.

Information sourced from Uniprot.org