Anti-T-Cell receptor antibody [TRIM-04] (STJ16100480)

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STJ16100480-01
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Host: Mouse
Applications: FC/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-T-Cell receptor is suitable for use in Flow Cytometry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : TRIM-04
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Recombinant intracellular domain (aa 29-186) of human TRIM.
Background TRIM (T cell receptor-interacting molecule) , also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.

Information sourced from Uniprot.org