| Background | The R73-2b monoclonal antibody binds to an epitope of the constant region of the rat Alpha ß-T cell receptor and is able to activate rat T cells (Beun et al., 1993). The reactivity of R73-2b monoclonal antibody is rat strain-independent. R73-coated culture flasks induce rat T cell proliferation (Beun et al., 1993). This monoclonal antibody is an IgG2b isotype switch variant (Beun et al., 1993) of the well-known R73 IgG1 monoclonal antibody that is specific for the rat Alpha ß-T cell receptor (Hünig et al. 1989). |
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