| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | SYTL4 |
| Gene ID: | 94121 |
| Uniprot ID: | SYTL4_HUMAN |
| Immunogen Region: | 50-280 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-280 of human SYTL4 (NP_542775.2). |
| Immunogen Sequence: | GAKRGSQHYSDRTCARCQES LGRLSPKTNTCRGCNHLVCR DCRIQESNGTWRCKVCAKEI ELKKATGDWFYDQKVNRFAY RTGSEIIRMSLRHKPAVSKR ETVGQSLLHQTQMGDIWPGR KIIQERQKEPSVLFEVPKLK SGKSALEAESESLDSFTADS DSTSRRDSLDKSGLFPEWKK MSAPKSQVEKETQPGGQNVV FVDEGEMIFKKNTRKILRPS EYTKSVIDLRP |
| Function | Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner. |
| Protein Name | Synaptotagmin-Like Protein 4Exophilin-2Granuphilin |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | MembranePeripheral Membrane ProteinCell MembraneCytoplasmic VesicleSecretory Vesicle MembraneDetected Close To The Plasma Membrane And On Secretory GranulesIn PancreasInteracts With Insulin-Containing Vesicles |
| Alternative Antibody Names | Anti-Synaptotagmin-Like Protein 4 antibodyAnti-Exophilin-2 antibodyAnti-Granuphilin antibodyAnti-SYTL4 antibody |
Information sourced from Uniprot.org