| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYT3 |
| Gene ID: | 84258 |
| Uniprot ID: | SYT3_HUMAN |
| Immunogen Region: | 449-590 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 449-590 of human SYT3 (NP_115674.1). |
| Immunogen Sequence: | TVTIIKASNLKAMDLTGFSD PYVKASLISEGRRLKKRKTS IKKNTLNPTYNEALVFDVAP ESVENVGLSIAVVDYDCIGH NEVIGVCRVGPDAADPHGRE HWAEMLANPRKPVEHWHQLV EEKTVTSFTKGSKGLSEKEN SE |
| Tissue Specificity | Expressed in melanocytes. |
| Function | Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes.both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Synaptotagmin-3Synaptotagmin IiiSytiii |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinCytoplasmic VesicleSecretory Vesicle Membrane |
| Alternative Antibody Names | Anti-Synaptotagmin-3 antibodyAnti-Synaptotagmin Iii antibodyAnti-Sytiii antibodyAnti-SYT3 antibody |
Information sourced from Uniprot.org