• Western blot analysis of lysates from U-251MG cells, using PCOLCE Rabbit polyclonal antibody (STJ117493) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-PCOLCE antibody (170-449) (STJ117493)

SKU:
STJ117493

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PCOLCE (170-449) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PCOLCE
Gene ID: 5118
Uniprot ID: PCOC1_HUMAN
Immunogen Region: 170-449
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-449 of human PCOLCE (NP_002584.2).
Immunogen Sequence: LTTPNWPESDYPPGISCSWH IIAPPDQVIALTFEKFDLEP DTYCRYDSVSVFNGAVSDDS RRLGKFCGDAVPGSISSEGN ELLVQFVSDLSVTADGFSAS YKTLPRGTAKEGQGPGPKRG TEPKVKLPPKSQPPEKTEES PSAPDAPTCPKQCRRTGTLQ SNFCASSLVVTATVKSMVRE PGEGLAVTVSLIGAYKTGGL DLPSPPTGASLKFYVPCKQC PPMKKGVSYLLMGQVEENR
Post Translational Modifications C-terminally processed at multiple positions.
Function Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.
Protein Name Procollagen C-Endopeptidase Enhancer 1
Procollagen Cooh-Terminal Proteinase Enhancer 1
Pcpe-1
Procollagen C-Proteinase Enhancer 1
Type 1 Procollagen C-Proteinase Enhancer Protein
Type I Procollagen Cooh-Terminal Proteinase Enhancer
Database Links Reactome: R-HSA-1650814
Reactome: R-HSA-2243919
Cellular Localisation Secreted
Alternative Antibody Names Anti-Procollagen C-Endopeptidase Enhancer 1 antibody
Anti-Procollagen Cooh-Terminal Proteinase Enhancer 1 antibody
Anti-Pcpe-1 antibody
Anti-Procollagen C-Proteinase Enhancer 1 antibody
Anti-Type 1 Procollagen C-Proteinase Enhancer Protein antibody
Anti-Type I Procollagen Cooh-Terminal Proteinase Enhancer antibody
Anti-PCOLCE antibody
Anti-PCPE1 antibody

Information sourced from Uniprot.org

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