| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SYT3 (449-590) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SYT3 |
| Gene ID: |
84258 |
| Uniprot ID: |
SYT3_HUMAN |
| Immunogen Region: |
449-590 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 449-590 of human SYT3 (NP_115674.1). |
| Immunogen Sequence: |
TVTIIKASNLKAMDLTGFSD PYVKASLISEGRRLKKRKTS IKKNTLNPTYNEALVFDVAP ESVENVGLSIAVVDYDCIGH NEVIGVCRVGPDAADPHGRE HWAEMLANPRKPVEHWHQLV EEKTVTSFTKGSKGLSEKEN SE |
| Tissue Specificity | Expressed in melanocytes. |
| Function | Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes.both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Synaptotagmin-3Synaptotagmin IiiSytiii |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinCytoplasmic VesicleSecretory Vesicle Membrane |
| Alternative Antibody Names | Anti-Synaptotagmin-3 antibodyAnti-Synaptotagmin Iii antibodyAnti-Sytiii antibodyAnti-SYT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
