Anti-Syntaxin 3 antibody (STJA0037515)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenPeptide
General Information
| Short Description | Rabbit monoclonal anti-Syntaxin 3 for use in WB, IHC-F, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB-1:500-1:1000IHC-1:50-1:100IF-1:50-1:200 |
| Formulation | Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | STX3 |
| Gene ID | 6809 |
| Uniprot ID | STX3_HUMAN |
| Immunogen | Peptide |
Additional Info
| Tissue Specificity | Isoform A: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle. Isoform B: Expressed only in the retina. Isoform 3: Ubiquitously expressed. |
| Function | Potentially involved in docking of synaptic vesicles at presynaptic active zones. Apical receptor involved in membrane fusion of apical vesicles. Isoform B: Essential for survival of retinal photoreceetors. Isoform 3: Functions as a regulator of gene expression. |
| Protein Name | Syntaxin-3 |
| Database Links | Reactome: R-HSA-449836 |
| Cellular Localisation | Isoform A: Apical Cell MembraneSingle-Pass Type Iv Membrane ProteinLocalized To The Inner And Outer Plexiform LayersThe Cell Body And The Inner Segments Of PhotoreceptorsIsoform 3: Nucleus |
| Alternative Antibody Names | Anti-Syntaxin-3 antibodyAnti-STX3 antibodyAnti-STX3A antibody |
Information sourced from Uniprot.org