Anti-SYNM antibody (STJA0007670)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SYNM
General Information
| Short Description | Rabbit polyclonal anti-Synemin for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SYNM |
| Gene ID | 23336 |
| Uniprot ID | SYNEM_HUMAN |
| Immunogen | Synthesized peptide derived from human SYNM |
| Specificity | This antibody detects endogenous levels of SYNM at Human, Mouse |
Additional Info
| Function | Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteromeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteromeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells. |
| Protein Name | SyneminDesmuslin |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionAdherens JunctionThere Are At Least Two Distinct Synm SubpopulationsOne In Which Symn Interacts With Des Within The Z-LinesAnd Another In Which It Interacts With Both Dtna And Des At The Costamere |
| Alternative Antibody Names | Anti-Synemin antibodyAnti-Desmuslin antibodyAnti-SYNM antibodyAnti-DMN antibodyAnti-KIAA0353 antibodyAnti-SYN antibody |
Information sourced from Uniprot.org