| Short Description : | Rabbit polyclonal anti-Synaptopodin for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 1000 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SYNPO |
| Gene ID: | 11346 |
| Uniprot ID: | SYNPO_HUMAN |
| Immunogen: | A synthetic peptide from rat Synaptopodin conjugated to blue carrier protein was used as the antigen. The peptide is homologous in human and mouse. |
| Specificity: | Specific for SYNPO. |
| Post Translational Modifications | O-glycosylated. |
| Function | Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity. |
| Protein Name | Synaptopodin |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionTight JunctionPerikaryonCell ProjectionDendritic SpinePostsynaptic DensitySynapseCytosolLocalized At The Tight Junction Of CellsIn BrainLocalized To The Postsynaptic Densities And In The PerikaryaAssociated With Dendritic Spines Of A Subset Of Synapses |
| Alternative Antibody Names | Anti-Synaptopodin antibodyAnti-SYNPO antibodyAnti-KIAA1029 antibody |
Information sourced from Uniprot.org
![Anti-Synaptopodin antibody [SM5224] (STJA0005224)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/180261/403796/STJA0005224_1__11694.1738950766.png?c=1 "Anti-Synaptopodin antibody [SM5224] (STJA0005224)")
