Anti-Synaptopodin antibody (STJ13100352)

SKU:
STJ13100352-100

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Host: Rabbit
Applications: IHC/WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Synaptopodin is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A dilution of 1: 1000 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: SYNPO
Gene ID: 11346
Uniprot ID: SYNPO_HUMAN
Specificity: Specific for SYNPO.
Immunogen: A synthetic peptide from rat Synaptopodin conjugated to blue carrier protein was used as the antigen. The peptide is homologous in human and mouse.
Post Translational Modifications O-glycosylated.
Function Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
Protein Name Synaptopodin
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Tight Junction
Perikaryon
Cell Projection
Dendritic Spine
Postsynaptic Density
Synapse
Cytosol
Localized At The Tight Junction Of Cells
In Brain
Localized To The Postsynaptic Densities And In The Perikarya
Associated With Dendritic Spines Of A Subset Of Synapses
Alternative Antibody Names Anti-Synaptopodin antibody
Anti-SYNPO antibody
Anti-KIAA1029 antibody

Information sourced from Uniprot.org

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