Anti-SULT1C2 antibody (STJA0007035)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SULT1C2
General Information
| Short Description | Rabbit polyclonal anti-Sulfotransferase 1C2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SULT1C2 |
| Gene ID | 6819 |
| Uniprot ID | ST1C2_HUMAN |
| Immunogen | Synthesized peptide derived from human SULT1C2 |
| Specificity | This antibody detects endogenous levels of SULT1C2 at Human, Mouse, Rat |
Additional Info
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the sulfate conjugation of phenolic compounds. Does not transfer sulfate to steroids, dopamine, acetaminophen, or alpha-naphthol. Except in mitochondria, where it can add sulfate to cholesterol producing cholesterol sulfate, which alters mitochondrial membrane organization, and impacts protein complex mobility increasing state-III respiration, thereby modulating mitochondrial respiration. Catalyzes the sulfation of the carcinogenic N-hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis. |
| Protein Name | Sulfotransferase 1c2St1c2Sulfotransferase 1c1Sult1c#1Humsultc2 |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | CytoplasmLysosomeMitochondrion |
| Alternative Antibody Names | Anti-Sulfotransferase 1c2 antibodyAnti-St1c2 antibodyAnti-Sulfotransferase 1c1 antibodyAnti-Sult1c#1 antibodyAnti-Humsultc2 antibodyAnti-SULT1C2 antibodyAnti-SULT1C1 antibody |
Information sourced from Uniprot.org