Anti-SULT1A3 antibody (1-100) (STJ114235)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SULT1A3 (1-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SULT1A3 |
| Gene ID | 445329/6818 |
| Uniprot ID | ST1A3_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MELIQDTSRPPLEYVKGVPL IKYFAEALGPLQSFQARPDD LLINTYPKSGTTWVSQILDM IYQGGDLEKCNRAPIYVRVP FLEVNDPGEPSGLETLKDTP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SULT1A3 (NP_808220.1). |
Additional Info
| Tissue Specificity | Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, (R)-adrenaline/epinephrine, (R)-noradrenaline/norepinephrine and serotonin) and phenolic and catechol drugs. Catalyzes the sulfation of T4 (L-thyroxine/3,5,3',5'-tetraiodothyronine), T3 (3,5,3'-triiodothyronine), rT3 (3,3',5'-triiodothyronine) and 3,3'-T2 (3,3'-diiodothyronine), with a substrate preference of 3,3'-T2 > rT3 > T3 > T4. |
| Protein Name | Sulfotransferase 1a3St1a3Aryl Sulfotransferase 1a3/1a4Catecholamine-Sulfating Phenol SulfotransferaseHast3M-PstMonoamine-Sulfating Phenol SulfotransferasePlacental Estrogen SulfotransferaseSulfotransferase 1a3/1a4Sulfotransferase - Monoamine-PreferringThermolabile Phenol SulfotransferaseTl-Pst |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-381038Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sulfotransferase 1a3 antibodyAnti-St1a3 antibodyAnti-Aryl Sulfotransferase 1a3/1a4 antibodyAnti-Catecholamine-Sulfating Phenol Sulfotransferase antibodyAnti-Hast3 antibodyAnti-M-Pst antibodyAnti-Monoamine-Sulfating Phenol Sulfotransferase antibodyAnti-Placental Estrogen Sulfotransferase antibodyAnti-Sulfotransferase 1a3/1a4 antibodyAnti-Sulfotransferase - Monoamine-Preferring antibodyAnti-Thermolabile Phenol Sulfotransferase antibodyAnti-Tl-Pst antibodyAnti-SULT1A3 antibodyAnti-STM antibody |
Information sourced from Uniprot.org