| Post Translational Modifications | Processing by furin produces a secreted form. Glycosylation at Ser-583 negatively regulates its N-acetylglucosamine-6-sulfatase and arylsulfatase activities. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. |
| Protein Name | Extracellular Sulfatase Sulf-2Hsulf-2ArylsulfataseN-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form |
| Database Links | |
| Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusGolgi StackCell SurfaceExtracellular Sulfatase Sulf-2 Secreted Form: Secreted |
| Alternative Antibody Names | Anti-Extracellular Sulfatase Sulf-2 antibodyAnti-Hsulf-2 antibodyAnti-Arylsulfatase antibodyAnti-N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form antibodyAnti-SULF2 antibodyAnti-KIAA1247 antibodyAnti-UNQ559 antibodyAnti-PRO1120 antibody |
Information sourced from Uniprot.org
