Anti-SULF2 antibody (690-740) (STJA0006517)

SKU:
STJA0006517
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Extracellular sulfatase Sulf-2 (690-740) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SULF2
Gene ID: 55959
Uniprot ID: SULF2_HUMAN
Immunogen Region: 690-740
Specificity: This antibody detects endogenous levels of human SULF2
Immunogen: Synthesized peptide derived from human SULF2 AA range: 690-740
Post Translational Modifications Processing by furin produces a secreted form. Glycosylation at Ser-583 negatively regulates its N-acetylglucosamine-6-sulfatase and arylsulfatase activities. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Function Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
Protein Name Extracellular Sulfatase Sulf-2
Hsulf-2
Arylsulfatase
N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form
Cellular Localisation Endoplasmic Reticulum
Golgi Apparatus
Golgi Stack
Cell Surface
Extracellular Sulfatase Sulf-2 Secreted Form: Secreted
Alternative Antibody Names Anti-Extracellular Sulfatase Sulf-2 antibody
Anti-Hsulf-2 antibody
Anti-Arylsulfatase antibody
Anti-N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form antibody
Anti-SULF2 antibody
Anti-KIAA1247 antibody
Anti-UNQ559 antibody
Anti-PRO1120 antibody

Information sourced from Uniprot.org

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