| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-SUGT1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 7B4 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Purification: | Affinity Purified |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | SUGT1 |
| Gene ID: | 10910 |
| Uniprot ID: | SGT1_HUMAN |
| Immunogen: | Full length human recombinant protein of human SUGT1 produced in E.coli. |
| Post Translational Modifications | Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex. |
| Function | May play a role in ubiquitination and subsequent proteasomal degradation of target proteins. |
| Protein Name | Protein Sgt1 HomologProtein 40-6-3Sgt1Suppressor Of G2 Allele Of Skp1 Homolog |
| Database Links | Reactome: R-HSA-844456Reactome: R-HSA-9660826 |
| Cellular Localisation | CytoplasmNucleusTranslocates To The Nucleus Upon Heat ShockRequiring S100a6 |
| Alternative Antibody Names | Anti-Protein Sgt1 Homolog antibodyAnti-Protein 40-6-3 antibodyAnti-Sgt1 antibodyAnti-Suppressor Of G2 Allele Of Skp1 Homolog antibodyAnti-SUGT1 antibody |
Information sourced from Uniprot.org