• Western blot analysis of various lysates, using STX6 Rabbit polyclonal antibody (STJ118716) at 1:800 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-STX6 antibody (1-234) (STJ118716)

SKU:
STJ118716

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-STX6 (1-234) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STX6
Gene ID: 10228
Uniprot ID: STX6_HUMAN
Immunogen Region: 1-234
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human STX6 (NP_005810.1).
Immunogen Sequence: MSMEDPFFVVKGEVQKAVNT AQGLFQRWTELLQDPSTATR EEIDWTTNELRNNLRSIEWD LEDLDETISIVEANPRKFNL DATELSIRKAFITSTRQVVR DMKDQMSTSSVQALAERKNR QALLGDSGSQNWSTGTTDKY GRLDRELQRANSHFIEEQQA QQQLIVEQQDEQLELVSGSI GVLKNMSQRIGGELEEQAVM LEDFSHELESTQSRLDNVMK KLAKVSHMTSDRRQ
Function SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway.
Protein Name Syntaxin-6
Database Links Reactome: R-HSA-6811438
Reactome: R-HSA-6811440
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Iv Membrane Protein
Golgi Apparatus
Trans-Golgi Network Membrane
Recycling Endosome Membrane
Alternative Antibody Names Anti-Syntaxin-6 antibody
Anti-STX6 antibody

Information sourced from Uniprot.org

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