| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STX6 |
| Gene ID: | 10228 |
| Uniprot ID: | STX6_HUMAN |
| Immunogen Region: | 1-234 |
| Immunogen Sequence: | MSMEDPFFVVKGEVQKAVNT AQGLFQRWTELLQDPSTATR EEIDWTTNELRNNLRSIEWD LEDLDETISIVEANPRKFNL DATELSIRKAFITSTRQVVR DMKDQMSTSSVQALAERKNR QALLGDSGSQNWSTGTTDKY GRLDRELQRANSHFIEEQQA QQQLIVEQQDEQLELVSGSI GVLKNMSQRIGGELEEQAVM LEDFSHELESTQSRLDNVMK KLAKVSHMTSDRRQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human STX6 (NP_005810.1). |
| Function | SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. |
| Protein Name | Syntaxin-6 |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-6811440 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Iv Membrane ProteinGolgi ApparatusTrans-Golgi Network MembraneRecycling Endosome Membrane |
| Alternative Antibody Names | Anti-Syntaxin-6 antibodyAnti-STX6 antibody |
Information sourced from Uniprot.org
