| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Syntaxin-1B is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STX1B |
| Gene ID: | 112755 |
| Uniprot ID: | STX1B_HUMAN |
| Specificity: | This antibody detects endogenous levels of Syntaxin 1A/Syntaxin 1B at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human Syntaxin 1A/Syntaxin 1B |
| Function | Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. |
| Protein Name | Syntaxin-1b Syntaxin-1b1 Syntaxin-1b2 |
| Database Links | Reactome: R-HSA-5250971 Reactome: R-HSA-5682910 |
| Cellular Localisation | Isoform 1: Membrane Single-Pass Type Iv Membrane Protein Isoform 2: Nucleus Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Spindle Colocalizes With Lamin A/C And Numa In Interphasic Nuclei And With Numa And Gamma-Tubulin In The Pericentrosomal Region Of The Mitotic Spindle In Dividing Cells |
| Alternative Antibody Names | Anti-Syntaxin-1b antibody Anti-Syntaxin-1b1 antibody Anti-Syntaxin-1b2 antibody Anti-STX1B antibody Anti-STX1B1 antibody Anti-STX1B2 antibody |
Information sourced from Uniprot.org