Anti-STRA8 antibody (70-81) (STJ72807)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-STRA8 (70-81) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Preliminary experiments gave an approx 90kDa band in Rat Duodenum and Testis lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the lite |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | STRA8 |
| Gene ID | 346673 |
| Uniprot ID | STRA8_HUMAN |
| Accession Number | NP_872295.1 |
| Immunogen Region | 70-81 |
| Immunogen Sequence | NNLRKTVYSQSD |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis. |
| Protein Name | Stimulated By Retinoic Acid Gene 8 Protein Homolog |
| Cellular Localisation | CytoplasmNucleusShuttles Between Nucleus And CytoplasmNuclear Export Is Xpo1-Dependent |
| Alternative Antibody Names | Anti-Stimulated By Retinoic Acid Gene 8 Protein Homolog antibodyAnti-STRA8 antibody |
Information sourced from Uniprot.org