Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Stimulated by retinoic acid gene 8 protein homolog (151-200 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
STRA8 |
Gene ID: |
346673 |
Uniprot ID: |
STRA8_HUMAN |
Immunogen Region: |
151-200 aa |
Specificity: |
Stra8 Polyclonal Antibody detects endogenous levels of Stra8 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human STRA8 at the amino acid range 151-200 |
Post Translational Modifications | Phosphorylated. |
Function | Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis. |
Protein Name | Stimulated By Retinoic Acid Gene 8 Protein Homolog |
Cellular Localisation | CytoplasmNucleusShuttles Between Nucleus And CytoplasmNuclear Export Is Xpo1-Dependent |
Alternative Antibody Names | Anti-Stimulated By Retinoic Acid Gene 8 Protein Homolog antibodyAnti-STRA8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance