Host: | Rabbit |
Applications: | WB/IF/FC/ELISA/IHC |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Stonin-2 (47-97 aa) is suitable for use in Western Blot, Immunofluorescence, Flow Cytometry, ELISA and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000IF ICC 1:50-200ELISA 1:2000-20000IHC-P 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | STON2 |
Gene ID: | 85439 |
Uniprot ID: | STON2_HUMAN |
Immunogen Region: | 47-97 aa |
Specificity: | This antibody detects endogenous levels of STON2 at Human/Mouse |
Immunogen: | Synthesized peptide derived from the human STON2 at the amino acid range 47-97 |
Post Translational Modifications | Phosphorylated in vitro by PKD. Neddylated.deneddylated via its interaction with the COP9 signalosome (CSN) complex through TOR1A and COPS4. Ubiquitinated.leading to its degradation. |
Function | Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating. |
Protein Name | Stonin-2Stoned B |
Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
Cellular Localisation | CytoplasmMembraneSynapseSynaptosomeSome Fraction Is Membrane-Associated |
Alternative Antibody Names | Anti-Stonin-2 antibodyAnti-Stoned B antibodyAnti-STON2 antibodyAnti-STN2 antibodyAnti-STNB antibody |
Information sourced from Uniprot.org