Anti-Stomatin antibody (N-Term) (STJ72960)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Stomatin (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 30kDa band observed in Human Erythrocytes, Spleen, Bone Marrow and Lung lysates (calculated MW of 31.7kDa according to NP_004090.4). Recommended concentration: 0.1-0.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | STOM |
| Gene ID | 2040 |
| Uniprot ID | STOM_HUMAN |
| Accession Number | NP_004090.4; NP_937837.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | EKRHTRDSEAQR |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_004090.4; NP_937837.1). |
Additional Info
| Function | Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. |
| Protein Name | StomatinErythrocyte Band 7 Integral Membrane ProteinErythrocyte Membrane Protein Band 7.2Protein 7.2b |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013406Reactome: R-HSA-9013407Reactome: R-HSA-9013409 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonLipid-AnchorMembrane RaftMelanosomeCytoplasmic VesicleLocalizes To Juxtanuclear Structure Probably Derived From The Golgi ApparatusColocalizes With Cortical Actin Microfilaments At Small Plasma Membrane ProtrusionsAssociates With Alpha-Granular Lipid RaftsTranslocates From The Alpha-Granular Lipid Rafts To The Cell Membrane On Thrombin Activation And Selectively Enriched In Released MicrovesiclesIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Stomatin antibodyAnti-Erythrocyte Band 7 Integral Membrane Protein antibodyAnti-Erythrocyte Membrane Protein Band 7.2 antibodyAnti-Protein 7.2b antibodyAnti-STOM antibodyAnti-BND7 antibodyAnti-EPB72 antibody |
Information sourced from Uniprot.org