| Host: |
Mouse |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Stathmin (1-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ABT266 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2ak |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: |
IHC-P 1:100-500WB 1:200-1000IF 1:100-500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STMN1 |
| Gene ID: |
3925 |
| Uniprot ID: |
STMN1_HUMAN |
| Immunogen Region: |
1-100 aa |
| Specificity: |
The antibody can specifically recognize human Stathmin protein. In western blotting of HepG2 cell lysate, the antibody can label a 17KDa band corresponding to Stathmin. |
| Immunogen: |
Synthesized peptide derived from the human Stathmin at the amino acid range 1-100 |
| Post Translational Modifications | Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization. Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity. |
| Function | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear. |
| Protein Name | StathminLeukemia-Associated Phosphoprotein P18MetablastinOncoprotein 18Op18Phosphoprotein P19Pp19ProsolinProtein Pr22Pp17 |
| Database Links | Reactome: R-HSA-1251985 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Stathmin antibodyAnti-Leukemia-Associated Phosphoprotein P18 antibodyAnti-Metablastin antibodyAnti-Oncoprotein 18 antibodyAnti-Op18 antibodyAnti-Phosphoprotein P19 antibodyAnti-Pp19 antibodyAnti-Prosolin antibodyAnti-Protein Pr22 antibodyAnti-Pp17 antibodyAnti-STMN1 antibodyAnti-C1orf215 antibodyAnti-LAP18 antibodyAnti-OP18 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
