| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Serine/threonine-protein kinase 33 (N-Term) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STK33 |
| Gene ID: | 65975 |
| Uniprot ID: | STK33_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | STK33 Polyclonal Antibody detects endogenous levels of STK33 protein. |
| Immunogen: | Synthesized peptide derived from the N-terminal region of human STK33. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Serine/threonine protein kinase required for spermatid differentiation and male fertility. Promotes sperm flagella assembly during spermatogenesis by mediating phosphorylation of fibrous sheath proteins AKAP3 and AKAP4. Also phosphorylates vimentin/VIM, thereby regulating the dynamic behavior of the intermediate filament cytoskeleton. |
| Protein Name | Serine/Threonine-Protein Kinase 33 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonPerinuclear RegionColocalizes With The Caudal End Of The ManchetteA Transient Structure That Guides Tail Elongation In Elongating Spermatids |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase 33 antibodyAnti-STK33 antibody |
Information sourced from Uniprot.org
