| Function | Serine/threonine-protein kinase that acts as a mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation. |
| Protein Name | Serine/Threonine-Protein Kinase 26Mst3 And Sok1-Related KinaseMammalian Ste20-Like Protein Kinase 4Mst-4Ste20-Like Kinase Mst4Serine/Threonine-Protein Kinase Mask |
| Database Links | Reactome: R-HSA-111465 |
| Cellular Localisation | CytoplasmGolgi ApparatusColocalized With Ripor1 In The Golgi Of Serum-Starved Cells And Relocated To Cytoplasmic PunctaeProbably Vesicular CompartmentsAlong With Ripor1 Upon Serum Stimulation In A Rho- And Pdcd10-Dependent Manner |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase 26 antibodyAnti-Mst3 And Sok1-Related Kinase antibodyAnti-Mammalian Ste20-Like Protein Kinase 4 antibodyAnti-Mst-4 antibodyAnti-Ste20-Like Kinase Mst4 antibodyAnti-Serine/Threonine-Protein Kinase Mask antibodyAnti-STK26 antibodyAnti-MASK antibodyAnti-MST4 antibody |
Information sourced from Uniprot.org
