Anti-STEAP4 antibody (201-250 aa) (STJ95801)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human STEAP4 at the amino acid range 201-250
General Information
| Short Description | Rabbit polyclonal anti-Metalloreductase STEAP4 (201-250 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STEAP4 |
| Gene ID | 79689 |
| Uniprot ID | STEA4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human STEAP4 at the amino acid range 201-250 |
| Immunogen Region | 201-250 aa |
| Specificity | STAMP2 Polyclonal Antibody detects endogenous levels of STAMP2 protein. |
Additional Info
| Function | Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. |
| Protein Name | Metalloreductase Steap4Six-Transmembrane Epithelial Antigen Of Prostate 4Sixtransmembrane Protein Of Prostate 2Tumor Necrosis Factor - Alpha-Induced Protein 9 |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneEarly Endosome Membrane |
| Alternative Antibody Names | Anti-Metalloreductase Steap4 antibodyAnti-Six-Transmembrane Epithelial Antigen Of Prostate 4 antibodyAnti-Sixtransmembrane Protein Of Prostate 2 antibodyAnti-Tumor Necrosis Factor - Alpha-Induced Protein 9 antibodyAnti-STEAP4 antibodyAnti-STAMP2 antibodyAnti-TNFAIP9 antibody |
Information sourced from Uniprot.org