Anti-STEAP1 antibody (1-80) (STJ119729)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal STEAP1 (1-80) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STEAP1 |
| Gene ID | 26872 |
| Uniprot ID | STEA1_HUMAN |
| Immunogen Region | 1-80 |
| Immunogen Sequence | MESRKDITNQEELWKMKPRR NLEEDDYLHKDTGETSMLKR PVLLHLHQTAHADEFDCPSE LQHTQELFPQWHLPIKIAAI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human STEAP1 (NP_036581.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. Highly expressed in prostate tumors. |
| Function | Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH. Promotes Fe(3+) reduction when fused to the NADPH-binding domain of STEAP4. |
| Protein Name | Steap1 ProteinSix-Transmembrane Epithelial Antigen Of Prostate 1 |
| Database Links | |
| Cellular Localisation | Endosome MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Steap1 Protein antibodyAnti-Six-Transmembrane Epithelial Antigen Of Prostate 1 antibodyAnti-STEAP1 antibodyAnti-PRSS24 antibodyAnti-STEAP antibody |
Information sourced from Uniprot.org