| Host: |
Chicken |
| Applications: |
ELISA/IHC/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Chicken polyclonal antibody anti-STAT6 (655-705) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgY |
| Purification: |
Affinity Purified |
| Concentration: |
0.5 µg/µl |
| Dilution Range: |
WB: 1:500ELISA: 1:10, 000IP: 1:150IHC: 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
STAT6 |
| Gene ID: |
6778 |
| Uniprot ID: |
STAT6_HUMAN |
| Immunogen Region: |
655-705 |
| Immunogen: |
Synthetic peptide taken within amino acid region 655-705 on human Signal transducer and activator of transcription 6 protein. |
| Post Translational Modifications | Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4. Tyrosine phosphorylated following stimulation by IL3/interleukin-3. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. Mono-ADP-ribosylated by PARP14. |
| Function | Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. |
| Protein Name | Signal Transducer And Activator Of Transcription 6Il-4 Stat |
| Database Links | Reactome: R-HSA-186763Reactome: R-HSA-3249367Reactome: R-HSA-6785807 |
| Cellular Localisation | CytoplasmNucleusTranslocated Into The Nucleus In Response To Phosphorylation |
| Alternative Antibody Names | Anti-Signal Transducer And Activator Of Transcription 6 antibodyAnti-Il-4 Stat antibodyAnti-STAT6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Anti-STAT6 antibody [EP325] (STJ16101442)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/151948/346996/STJ16101442_1__38182.1681999241.jpg?c=1 "Anti-STAT6 antibody [EP325] (STJ16101442)")
