| Short Description : | Rabbit monoclonal anti-Signal Transducer And Activator Of Transcription 5b for use in WB, IHC, IF, IP and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | PT0851R |
| Isotype: | IgGk |
| Conjugation: | Unconjugated |
| Purification: | Protein A |
| Dilution Range: | IHC 1:1000-1:5000WB 1:2000-1:10000IF 1:200-1:1000ELISA 1:5000-1:20000IP 1:50-1:200 |
| Formulation: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STAT5B |
| Gene ID: | 6777 |
| Uniprot ID: | STA5B_HUMAN |
| Specificity: | Endogenous |
| Function | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation. |
| Protein Name | Signal Transducer And Activator Of Transcription 5b |
| Database Links | Reactome: R-HSA-1170546Reactome: R-HSA-1266695Reactome: R-HSA-1433557Reactome: R-HSA-1839117Reactome: R-HSA-186763Reactome: R-HSA-2586552Reactome: R-HSA-512988Reactome: R-HSA-8854691Reactome: R-HSA-8983432Reactome: R-HSA-8985947Reactome: R-HSA-9020558Reactome: R-HSA-9020958Reactome: R-HSA-9027283Reactome: R-HSA-9645135Reactome: R-HSA-9670439Reactome: R-HSA-9674555Reactome: R-HSA-9702518Reactome: R-HSA-9703465Reactome: R-HSA-9705462Reactome: R-HSA-982772 |
| Cellular Localisation | CytoplasmNucleusTranslocated Into The Nucleus In Response To Phosphorylation |
| Alternative Antibody Names | Anti-Signal Transducer And Activator Of Transcription 5b antibodyAnti-STAT5B antibody |
Information sourced from Uniprot.org
