| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STAR |
| Gene ID: | 6770 |
| Uniprot ID: | STAR_HUMAN |
| Immunogen Region: | 64-285 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 64-285 of human StAR (NP_000340.2). |
| Immunogen Sequence: | EETLYSDQELAYLQQGEEAM QKALGILSNQEGWKKESQQD NGDKVMSKVVPDVGKVFRLE VVVDQPMERLYEELVERMEA MGEWNPNVKEIKVLQKIGKD TFITHELAAEAAGNLVGPRD FVSVRCAKRRGSTCVLAGMA TDFGNMPEQKGVIRAEHGPT CMVLHPLAGSPSKTKLTWLL SIDLKGWLPKSIINQVLSQT QVDFANHLRKRLESHPASEA RC |
| Tissue Specificity | Expressed in gonads, adrenal cortex and kidney. |
| Function | Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. |
| Protein Name | Steroidogenic Acute Regulatory Protein - MitochondrialStarStart Domain-Containing Protein 1Stard1 |
| Database Links | Reactome: R-HSA-196108Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Steroidogenic Acute Regulatory Protein - Mitochondrial antibodyAnti-Star antibodyAnti-Start Domain-Containing Protein 1 antibodyAnti-Stard1 antibodyAnti-STAR antibodyAnti-STARD1 antibody |
Information sourced from Uniprot.org