• Immunofluorescence analysis of A549. 1, primary Antibody was diluted at 1:200 (4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 488 Secondary antibody was diluted at 1:1000 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min.
  • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA, pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200 (4°C overnight. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-STAB2 antibody (980-1060 aa) (STJ192359)

SKU:
STJ192359

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Stabilin-2 (980-1060 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-300
IF 1:100-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STAB2
Gene ID: 55576
Uniprot ID: STAB2_HUMAN
Immunogen Region: 980-1060 aa
Specificity: STAB2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 980-1060
Post Translational Modifications Glycosylated. Proteolytically processed to yield a 190 kDa protein.
Function Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalization as well as HA and CS.
Protein Name Stabilin-2
Fas1 Egf-Like And X-Link Domain-Containing Adhesion Molecule 2
Fasciclin - Egf-Like - Laminin-Type Egf-Like And Link Domain-Containing Scavenger Receptor 2
Feel-2
Hyaluronan Receptor For Endocytosis Cleaved Into - 190 Kda Form Stabilin-2
190 Kda Hyaluronan Receptor For Endocytosis
Database Links Reactome: R-HSA-2160916
Reactome: R-HSA-3000497
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasm
Only A Small Amount Appears To Be Present At The Cell Surface
Alternative Antibody Names Anti-Stabilin-2 antibody
Anti-Fas1 Egf-Like And X-Link Domain-Containing Adhesion Molecule 2 antibody
Anti-Fasciclin - Egf-Like - Laminin-Type Egf-Like And Link Domain-Containing Scavenger Receptor 2 antibody
Anti-Feel-2 antibody
Anti-Hyaluronan Receptor For Endocytosis Cleaved Into - 190 Kda Form Stabilin-2 antibody
Anti-190 Kda Hyaluronan Receptor For Endocytosis antibody
Anti-STAB2 antibody
Anti-FEEL2 antibody
Anti-FELL antibody
Anti-FEX2 antibody
Anti-HARE antibody

Information sourced from Uniprot.org

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