Anti-ST6GALNAC1 antibody (STJA0007821)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ST6GALNAC1
General Information
| Short Description | Rabbit polyclonal anti-Alpha-N-acetylgalactosaminide alpha-2, 6-sialyltransferase 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ST6GALNAC1 |
| Gene ID | 55808 |
| Uniprot ID | SIA7A_HUMAN |
| Immunogen | Synthesized peptide derived from human ST6GALNAC1 |
| Specificity | This antibody detects endogenous levels of ST6GALNAC1 at Human, Mouse |
Additional Info
| Post Translational Modifications | Glycosylated.autosialylated. |
| Function | Protein sialyltransferase specifically expressed in goblet cells that plays a key role in intestinal host-commensal homeostasis. Conjugates sialic acid with an alpha-2-6 linkage to N-acetylgalactosamine (GalNAc) glycan chains linked to serine or threonine in glycoproteins. Catalyzes the formation of the sialyl-Tn (S-Tn) antigen, an antigen found in intestinal goblet cells, as well as ulcerative colitis (UC) and various cancers. Protein sialylation in globlet cells is essential for mucus integrity and is required to protect the intestinal mucus against excessive bacterial proteolytic degradation. |
| Protein Name | Alpha-N-Acetylgalactosaminide Alpha-2 -6-Sialyltransferase 1Galnac Alpha-2 -6-Sialyltransferase ISt6galnac ISt6galnac-ISt6galnaciHst6galnac-ISialyltransferase 7aSiat7-A |
| Database Links | Reactome: R-HSA-4085001 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-N-Acetylgalactosaminide Alpha-2 -6-Sialyltransferase 1 antibodyAnti-Galnac Alpha-2 -6-Sialyltransferase I antibodyAnti-St6galnac I antibodyAnti-St6galnac-I antibodyAnti-St6galnaci antibodyAnti-Hst6galnac-I antibodyAnti-Sialyltransferase 7a antibodyAnti-Siat7-A antibodyAnti-ST6GALNAC1 antibodyAnti-SIAT7A antibodyAnti-UNQ543 antibodyAnti-PRO848 antibody |
Information sourced from Uniprot.org